DANAZOL (Danocrine®) slows production of the female hormone estrogen. Danazol is a man-made steroid that has similar actions to androgens, or male sex hormones. Danazol relieves the symptoms of endometriosis by shrinking the abnormal tissue, which forms a lining to the womb. Danazol can reduce the growth of abnormal breast tissue and is helpful in the treatment of fibrocystic breast disease. Danazol also treats a disorder that affects both men and women called hereditary angioedema, which causes swelling and pain in the arms, legs, face, throat, colon, or reproductive (sex) organs.
Treating endometriosis, symptoms of fibrocystic breast disease, orgiant hives. It may also be used for other conditions as determined by your doctor.
Danazol is a synthetic steroid. It works by decreasing the level of certain hormones, which reduces the symptoms and severity of the diseases treated by Danazol.
Thus it is primarily used to treat nausea and vomiting, and to facilitate gastric emptying in patients with gastric stasis.
Do NOT use Danazol if:
you are allergic to any ingredient in Danazol
you are pregnant or breast-feeding
you have undiagnosed vaginal bleeding
you have the blood disease porphyria or severely decreased liver, kidney, or heart function
Contact your doctor or health care provider right away if any of these apply to you.
Before using Danazol :
Some medical conditions may interact with Danazol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are planning to become pregnant
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of blood clots or stroke, cancer, heart failure, heart disease, or liver or kidney problems
Some MEDICINES MAY INTERACT with Danazol. Tell your health care provider if you are taking any other medicines, especially any of the following:
Anticoagulants (eg, warfarin), carbamazepine, cyclosporine, or macrolide immunosuppressants (eg, tacrolimus) because the actions and side effects of these medicines may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Danazol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Danazol :
Use Danazol as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Danazol may be taken with or without food.
If you are being treated for endometriosis or fibrocystic breast disease, you should begin treatment during menstruation.
Endometriosis patients - You must take Danazol consistently for 3 to 6 months. It may be necessary to take Danazol for 9 months.
If you miss a dose of Danazol , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Danazol.
Important safety information:
Danazol may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Danazol. Using Danazol alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
Do not take more medicine than prescribed unless advised to do so by your doctor.
It may take several months for Danazol to work. Do not stop using Danazol without checking with your doctor.
Use a barrier contraceptive (birth control), such as a condom or diaphragm, while taking Danazol.
Diabetes patients - Danazol may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
LAB TESTS, including liver function tests and complete blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
Use Danazol with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Danazol if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Danazol is excreted in breast milk. Do not breast-feed while taking Danazol.
Possible side effects of Danazol :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Acne; changes in menstrual flow; changes in semen volume and sperm count; emotional problems; excessively oily skin; flushing; hair loss; nervousness; reduction in breast size; sweating; vaginal itching or dryness; voice changes (hoarseness, sore throat, change in pitch); weight gain.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal hair growth; arm or leg pain; breathing trouble; chest pain; dark urine; dizziness; fainting; headache; nausea; one-sided weakness; slurred speech; sore throat or fever; stomach pain; swelling; unusual bleeding or bruising; vision problems;
vomiting; yellowing of the skin or eyes.
What is the shelf life of the drugs?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
Very often our web site visitors ask us about generic medications. In this section we have placed some useful information about generic drugs in general and about the ones we have in our product list. Read more
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