Generic Zyban

Zyban

Generic name: Bupropion
Bupropion tablets

What are bupropion tablets?

BUPROPION (Wellbutrin®) is an antidepressant, a medicine that helps to lift mental depression. Bupropion acts differently from other antidepressants and may be useful for treating patients who have had unusual or limiting effects from other antidepressants. Occasionally bupropion is prescribed for other behavioral or emotional problems. Generic bupropion tablets are available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

frequently drink alcoholic beverages

an eating disorder, such as anorexia or bulimia

bipolar disorder or psychosis

heart disease, previous heart attack, or irregular heart beat

head injury or brain tumor

high blood pressure

kidney disease

liver disease

seizures (convulsions)

suicidal thoughts or a previous suicide attempt

Tourette's syndrome

use of sedatives

weight loss

an unusual or allergic reaction to bupropion, other medicines, foods, dyes, or preservatives

breast-feeding

pregnant or trying to become pregnant

How should I take this medicine?

Take bupropion tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. It is important to take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking the tablets except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is less than four hours to your next dose, take only that dose and skip the missed dose. Do not take double or extra doses.

What drug(s) may interact with bupropion?

NOTE: Do not take bupropion with other medicines containing bupropion, like Zyban®.
Other medicines that can interact with bupropion include:

alcohol

amphetamine

carbamazepine

cimetidine

cocaine

corticosteroids

dextroamphetamine

doxercalciferol

kava kava, Piper methysticum

levodopa or combination drugs containing levodopa

linezolid

medications or herbal products for weight control or appetite

medicines for mental depression, emotional, or psychotic disturbances

medicines for difficulty sleeping

medicines called MAO inhibitors-phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Eldepryl®)

nicotine

orphenadrine

phenobarbital

phenytoin

rifampin

ritonavir

some medicines for heart rhythm or blood pressure

some medicines for migraine headache (propranolol)

some medicines for pain, such as codeine

St. John's wort, Hypericum perforatum

theophylline

tramadol

valerian, Valeriana officinalis

valproic acid

warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. Also, tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking bupropion?

Side effects that you should report to your prescriber or health care professional as soon as possible:
Uncommon:

blurred vision

difficulty breathing or wheezing

fast or irregular heartbeat (palpitations)

increased blood pressure

hallucinations

redness, blistering, peeling or loosening of the skin, including inside the mouth

unusual tiredness or weakness
More common:

agitation, anxiety, or restlessness, especially in the first week of treatment or when doses are changed

confusion

seizures

skin rash, itching, hives

vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
Less common:

loss of appetite

loss of sexual drive

menstrual changes
More common:

change in taste

constipation

difficulty sleeping

dizziness

dry mouth

headache

increased sweating

nausea

tremor

weight loss

What should I watch for while taking bupropion?

Visit your prescriber or health care professional for regular checks on your progress. You may have to take bupropion for several days before you see the effects. If you have been taking bupropion for some time, do not suddenly stop taking it. Your prescriber or health care professional may want you to gradually reduce the dose; ask for advice.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of bupropion treatment or after a change in dose, call your doctor.

You may get dizzy or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how bupropion affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Alcohol may increase dizziness or drowsiness; avoid alcoholic drinks while taking bupropion. Drinking excessive alcoholic beverages, using sleeping or anxiety medicines, or quickly stopping the use of these agents while taking bupropion may increase your risk for a seizure (convulsion).

Bupropion can make your mouth dry. Chewing sugarless gum, sucking hard candy and drinking plenty of water will help.

Do not treat yourself for coughs, colds, or allergies without asking your prescriber or health care professional for advice. Also do not take any herbal or non-prescription medicines for weight loss without your prescribers advice. Some ingredients may increase possible side effects.

If you are going to have surgery, tell your prescriber or health care professional well before your scheduled surgery that you are taking bupropion.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F), away from direct sunlight and moisture. Keep tightly closed. Throw away any unused medicine after the expiration date.